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Learn about side effects, warnings, and dosage Depakote ER is not bioequivalent to delayed-release tabs on mg/mg basis. Depakote ER initial dose: 500 mg PO qDay for 1 week. The health and medical information provided here is for general purposes only and is not a substitute for the expertise and judgment of your physician, or other health care professional Similar Brand Name Drugs : Depakote ER: Oral tablet, extended release (500mg) | Generic Depakote Er 500mg Depakote ER: Oral tablet, extended release (250mg) Similar Generic Drugs : Divalproex Sodium: Oral tablet, extended release (500mg) | Divalproex Sodium: Oral tablet, extended release (250mg). Color white shape oblong imprint AN 757 This medicine is a white, oblong, coated, tablet imprinted with "AN 757". 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